56、教学大纲-肿瘤学理论Word文件下载.docx

1、第一章 癌症发病概况及防治战略2Chapter 1. Cancer Prevalence and Prevention Strategies2第二章 肿瘤的生物治疗3Chapter 2. Tumor Biotherapy4第三章 肿瘤病理学5Chapter 3. Oncologic Pathology6第四章 肿瘤临床诊断学概论7Chapter 4. Clinical Diagnosis of Cancer8第五章 肿瘤的夕卜科学总论9Chapter 5. Overview of Surgical Oncology9第六章肿瘤放射治疗学10Chapter 6. Radiation Oncolo

2、gy12第七章肿瘤化学治疗14Chapter 7. Management of Medical Oncology15第八节鼻咽癌16Chapter 8. Nasopharyngeal Carcinoma17第九章喉癌，甲状腺癌19Chapter 9. Laryngocarcinoma, Thyroid Cancer20第十章肺癌22Chapter 10. Lung Cancer23第十一章食管癌26Chapter 11. Esophageal Carcinoma27第十二章乳腺癌29Chapter 12. Breast Cancer30第十三章肝癌32Chapter 13. Primary L

3、iver Cancer33第十四章胃癌35Chapter 14. Gastric Cancer36第十五章结直肠癌37Chapter 15. Colorectal Cancer37第十六章 子宫颈癌38Chapter 16. Cervical Cancer40第十七章 淋巴瘤和终末期癌症病人处理41Chapter 17. Lymphoma and the Terminal Care for Cancer Patients42第一章癌症发病概况及防治战略时间分配：1学时一、教学目的：使临床医学生了解常见恶性肿瘤的流行趋势及其预防策略并培养其肿瘤预防意 识。二、教学基本要求：1. 牢固掌握：常见恶

4、性肿瘤防治原则；2. 一般掌握：恶性肿瘤常见致病因素；3. 一般了解：常见恶性肿瘤流行规律。三、教学内容：介绍肿瘤常见致病因素及其预防措施，肿瘤流行特征，特别是常见恶性肿瘤流行 趋势及变化原因；重点介绍癌症的防控原则，特别是一、二级预防的原则和效果；以 鼻咽癌、肝癌、食管癌等常见肿瘤说明恶性肿瘤防治工作的重要意义。四、重点与难点：1. 肿瘤常见致病因素及其预防措施，肿瘤流行特征，特别是常见恶性肿瘤流行趋势及变化原因；2. 癌症的防控原则。肿瘤预防研究部修订Chapter 1. Cancer Prevalence and Prevention StrategiesDuration: 1 clas

5、s hourI. ObjectivesThis chapter aims to help clinical students understand the epidemiology and prevention strategies of common malignant tumors and to develop cancer prevention consciousness.II. Requirementsi. Imperative understanding: the tumor prevention strategiesii. Intermediary understanding: t

6、he common causes or drivers of malignant tumorsiii. Basic understanding: the epidemiology of the common malignant tumorsIII. ContentsThis chapter covers various topics regarding the malignant tumor from multiple perspectives, ranges from the causes/drivers, epidemiological characteristics, and preve

7、ntion strategies. Among these above topics, cancer prevention strategies especially the principles and effects of primary and secondary cancer prevention strategies will be highlighted by the lecturer. The lecturer will also help the students to understand the importance of cancer prevention strateg

8、ies on malignant tumor control using nasopharyngeal carcinoma, liver tumor, and esophageal cancer control programs as examples.IV. Key Points and Difficult Pointsi. Common risk factors for tumors and their related prevention strategies; Epidemiological characteristics of malignant tumors, especially

9、 the epidemiological trend and their determinants of common malignant tumorsii. The principles of malignant tumor controlRevised by: Department of Cancer Prevention Research第二章肿瘤的生物治疗一、教学目的通过学习，掌握肿瘤生物治疗的概念、类型及临床应用进展。二、教学基本要求肿瘤生物治疗的常用方案，各自的优点和目前存在的主要问题肿瘤生物治疗（包括基因治疗）作为新型肿瘤治疗模式的现状肿瘤免疫治疗的策略和关键限制因素三、教学内容

10、1. 生物治疗在干预癌侵袭转移方面的应用前景；2. 肿瘤生物治疗的常用类型和各自特点；3, 基因治疗的原理及应用4. 肿瘤免疫治疗的原理、存在问题和目前的研究热点。四、重点与难点以过继性细胞治疗和checkpoint inhibitor为重点来阐述肿瘤生物治疗的优势 和存在问题。生物治疗中心修订Chapter 2. Tumor BiotherapyThis chapter aims to help students master the concept, types and clinical progress of tumor biotherapy. the categories of tum

11、or biotherapy, and its advantages and disadvantages the present situation of tumor biotherapy （including gene therapy） as a new mode of cancer treatments the strategies and the critical limiting factors of tumor immunotherapyi. The application prospect of tumor biotherapy in preventing the invasion

12、and metastasis of cancersii. The categories of tumor biotherapy and their characteristicsiii. The principles and applications of gene therapy in tumor treatmentiv. The principles, types, disadvantages and current research hotspots of tumor immunotherapyTake adoptive cell therapy and checkpoint inhib

13、itor as key points to introduce the advantages and disadvantages of tumor biotherapy. Department of Biotherapy第三章肿瘤的病理学诊断2学时病理学在肿瘤诊治中应用肿瘤病理学的基本理论、基本概念及基本方法；病理学在肿瘤诊治中的重要地位；病理新技术在病理肿瘤诊治中的新进展。1. 肿瘤病理学的基本理论及概念：肿瘤的概念；肿瘤病理形态学特征；肿瘤的分化 及分级；良恶性肿瘤的鉴别要点；肿瘤的生长与扩散转移；肿瘤的命名及分类； 交界性肿瘤；化生、单纯性增生、不典型增生、癌前病变、原位癌、浸润癌；肿

14、瘤分级与分期。2. 肿瘤病理诊断方法：组织病理学诊断及其相关方法（标本分类，常规组织病理染色 流程）；细胞学诊断价值及常用方法；术中冰冻切片和组织石蜡切片的方法及其应 用；组织化学、免疫组织化学、免疫荧光技术在病理诊断及治疗中的应用。3. 掌握病理报告解读。第一节重点：肿瘤病理学的基本理论及概念；难点：肿瘤形态学及生物学特征、良恶性肿瘤鉴别要点、肿瘤命名与分类、分级与 分期。第二节肿瘤病理诊断方法；组织标本分类、组织病理诊断流程、冰冻切片和组织石蜡切片的方法及其 应用、免疫组织化学技术及分子生物学技术在病理诊断及个体化治疗中的 作用。五、教学环节安排：思考题六、推荐阅读资料：Rosai J.

15、（Ed.） （2004）. Rosai and Ackerman s Surgical Pathology. 9th Edition. Elsevier, St Louis, Missouri.病理科修订Chapter 3. Oncologic Pathology 2 class hoursThis chapter aims to help students master the application of pathology in tumor diagnosis and treatment. the basic theories, concepts, and methods of onco

16、logic pathology the importance of pathology in tumor diagnosis and treatment the progress of pathology in tumor diagnosis and treatmenti. Master the basic theory and concept of oncologic pathology: concept of tumor, morphological characteristics of tumor, differentiation and grading of tumor, charac

17、teristics of benign versus malignant tumors, tumor growth and metastasis, nomenclature and classification of tumors, borderline tumor, metaplasia, simple hyperplasia, atypical hyperplasia, precancerous lesion, carcinoma in situ, invasive carcinoma, grading and staging of tumors.ii. Master the techni

18、que used in pathologic diagnosis of tumors: technology and methods of histopathology such as types of specimens and procedure of routine histological staining; techniques and application of cytological diagnosis; techniques and application of frozen section and paraffin section; technique applicatio

19、n of histochemistry, immunohistochemistry, and immunofluorescence in pathological diagnosis and treatmentiii. Master interpretation of pathological report.IV. Key points and Difficult PointsSection 1Key points: the basic theory and concept of oncologic pathologyDifficult points: the morphology and b

20、iological behavior of tumor, characteristics of benign versus malignant tumors, nomenclature and classification of tumors, grading and staging of tumorsSection 2 the techniques and methods of tumor pathology diagnosis the types of tissue samples, procedure of pathological diagnosis, method of frozen

21、 section and paraffin section and their application, application of molecular biology techniques in pathological diagnosis and individualized treatment.V Course ArrangementsCritical thinking.VI. References for Further Reading.Rosai J. （Ed.） （2004）. Rosai and Ackerman fs Surgical Pathology. 9th Editi

22、on. Elsevier, St Louis, Missouri. Department of Pathology第四章肿瘤临床诊断学概论一、教学基本要求：癌症的临床表现、肿瘤临床诊断的常用方法和诊断原则；肿瘤临床诊断方法中的所包含的具体内容、树立提高癌症警惕性的观 念，随时注意癌症存在的可能性；肿瘤的临床分期，肿瘤标记物检测方法。二、教学内容：1. 介绍肿瘤临床诊断中的常见方法：1） 询问病史2） 体格检查3） 常规化验4） 特殊检查5） 肿瘤标记物检测6） 病理检查7） 诊断性手术2. 介绍肿瘤的临床分期，TNM分期系统3. 重点介绍临床采集肿瘤病人病史、体格检查中的特殊性；体格检查时肿块

23、、淋巴 结转移的特点；特殊检查的适应症；强调病理检查的重要性，诊断性手术的适应症。三、重点与难点：肿瘤临床诊断的方法和原则；常见肿瘤典型临床表现，授课时应图文并茂，加强学生对肿瘤特殊的临床表现 的深刻印象。内科修订Chapter 4. Clinical Diagnosis of CancerI. Requirements the clinical manifestations of cancer, the common methods and principle for clinical diagnosis of cancer the contents of clinical diagnosi

24、s of cancer. The students are required to build up the idea of improving the vigilance of cancer. the clinical staging and tumor markers detectionII. Objectivesi. Introduce the common methods for clinical diagnosis of cancera） History inquiryb） Physical examinationc） Routine laboratory examinationd）

25、 Special examinatione） Tumor markersf） Pathologic examinationg） Diagnostic operation8ii. Introduce the clinical stage of the tumor and the TNM staging system.iii. Introduce the characteristics of history taking and physical examination, the feature of tumor mass and lymph nodes metastasis, the indic

26、ation for special examination, the importance of pathologic examination, the indication for diagnostic operation.III. Key Points and Difficult PointsKey Points: the common methods and principles or clinical diagnosis of cancerDifficult Points: the typical clinical manifestation of common tumors. Bot

27、h texts and graphics will help the students deepen their impression about the clinical manifestation of tumors. Department of Medical Oncology第五章肿瘤的外科学总论掌握肿瘤外科的治疗原则；各种手术术式的临床应用；肿瘤外科手术在肿瘤诊治中的地位。1. 肿瘤外科学的历史、发展过程和发展方向；2. 肿瘤外科治疗的地位、外科技术的特点；3. 肿瘤外科的治疗原则；4. 良性肿瘤的外科治疗；5. 恶性肿瘤的外科治疗：各种不同手术方式的临床应用；术前、术中、术后的注意 事项；肿瘤急诊的外科处理原则（包括出血、呼吸困难、梗阻、疼痛等）；6. 外科手术后修复与重建。三、重点与难点：肿瘤外科的治疗原则、肿瘤外科各种术式临床应用（举例说明）头颈科修订i. Imperative u