滨州市继续医学教育药学专业项目学习精神药物的治疗规范.docx

滨州市继续医学教育药学专业项目学习精神药物的治疗规范.docx

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滨州市继续医学教育药学专业项目学习精神药物的治疗规范

2013滨州市继续医学教育药学专业项目学习精神药物的治疗规范

Theuseofpsychotropicdrugsinspecificpopulations

C1,aspecialgroupofpsychotropicdrugs,doesnotinclude（）

A,theelderly

B,women

C,depressivepatients

D,children

C2,thefollowingaretheDdrugsinpregnancy

A,ammonianon-ketone

Bandamitriptyline

C,imipraminoxide

D,amitriptyline

D3,theincorrectuseofantipsychoticdrugsinelderlypatientsis（）

Apreventsorthostatichypotension

B,preventreflextachycardia

C,weshouldpayattentiontoextrapyramidaladversereactions

Dandtheelderlywereinsensitivetoanticholinergicadversereactions

C4,whichisincorrectforantipsychotictreatmentduringpregnancy

A,ifapregnancyrequirestreatment,anonantipsychoticmedicationshouldbegivenwithoutregardtoanticonvulsantmoodstabilizers

B,motherswhoareusingantipsychoticmedications,areontheirownandshouldbemonitoredforpossibleadverseeffectsifbreastfeedingisperformed

WhetherCandantipsychoticdrugsaresecretedinhumanmilkisunknown,butitisassumedthatallpsychotropicdrugsarenotsecretedinhumanmilk

Dandduringpregnancy,psychoticsymptomsmayworsenandmayrequiresometreatment

A,5,50%-75%ofindividualswithpostpartumdepressionappearin（）

A,1weekspostpartum

B,3weekspostpartum

C,postpartum,January

D,postpartum,March

C6,whichbelongstoadversedruginteractions,issusceptibletothecrowd

A,women

B,children

C,theelderly

D,depressivepatients

ThetreatmentfeaturesofD7andgeriatricschizophreniadonotinclude（）

A,securityisthemainidea

B,payattentiontothecombinationofotherdiseasesandmedications,andpayattentiontodruginteractions

Candstrengthenadversereactionmonitoring

ForDandcombinationdrugs,theinitialamountwaslowerthanthatofyoungeradults,andtheslowtitrationwasaddedtotheeffectivedose

D8,druguseforthetreatmentofschizophreniainchildrenisnotcorrect

A,sulpiride:

patientsover14yearsold

B,quetiapine:

schizophreniaandover10yearoldmanic/mixedtypeinchildrenover13yearsofage

C,aripiprazole:

schizophreniaandover10yearoldmanic/mixedtypeinchildrenover13yearsofage

Dandchlorpromazine:

canbeusedforseverebehavioraldisordersinchildrenovertheageof1.TheyarecontraindicatedinpatientswithReyesignsandareusuallyusedasfirst-lineagents

ThecharacteristicsofD9andchildhooddepressivedisorderinclude（）

TheincidenceofAandadolescentdepressionhasbeenincreasinginrecentyears

B,adolescentswithsocialanxietydisorderanddepressivesymptomswereatincreasedriskofdevelopingdepressivedisorderattheyouthstage

Candchildhoodandadolescentdepressionaredetrimentaltophysicalandpsychologicaldevelopment

D,themajorityofadolescentswithdepressionwillnotrelapseaftertreatment,andveryfewadolescentdepressivedisordersaresustainedintoadulthood

C10,followingthetreatmentofchildrenandadolescentswithdepressivedisorder,isincorrect

Aandcognitivebehavioraltherapycanreducedepressivesymptoms,speedupsymptoms,reducesuiciderates,andreducefunctionalimpairment

B,whenthedrugtreatmenttoalleviatesymptomsofdepression,andthencooperatewithpsychologicaltreatment,willenablepatientstorecognizethedisease,andenhancetheabilitytocopewithdifficultiesandsetbacksandself-confidence

C,childrenandadolescentshaveearlyonsetofdepression,

Shouldfirstrelysolelyondrugsorpsychotherapy

D,supportivecare,andfamilytherapyarealsoeffective

Antipsychoticdrugsafety

B1,thebestcourseofactionforpatientswithdrug-inducedweightgainis（）

A,immediatewithdrawal

B,lifestyleplusmetformin

C,lifestyle

D,metformin

InD2,themostobviousprolongationoftheQTintervalinthefollowingantipsychoticdrugsis（）

Aziprasidone

B,KuiLiuping

Candolanzapine

D

D3,principlesofsafeuseofantipsychoticdrugs,including（）

A,trytouseantipsychoticdrugsasmuchaspossible

Bandmultidrugapplicationsshouldpayattentiontopossibleinteractions

CfocusesonmonitoringEPS/TD.,bloodsugarandQT/QTc

Dandaboveallinclude

C4,themostappropriatemeasureforhyperprolactinemiainthetreatmentofrisperidoneis（）

A,drugreduction

B,immediatewithdrawal

Candaripiprazole

Dplusplacebo

D5,anantipsychoticdrugthatcausesweightgain,includes（）

A,thefirst3monthsareobvious,laterintheplateau

Bisassociatedwithtreatmenttime,irrespectiveofdosage

Canddrugsusceptibility:

newdrugsaremoreimportantthantraditionaldrugs

Dandaboveallinclude

B,6,isanantipsychoticthatismorelikelytocauseweightgainandabnormalglucoseandlipidmetabolism

A,thefirstgenerationofantipsychoticdrugs

Bandsecondgenerationantipsychotics

C,traditionalantipsychoticdrugs

D,haloperidol

A7,themostobviousincreaseinbodyweightcausedbythefollowingantipsychoticdrugsis（）

Aandclozapine

Bandrisperidone

Cziprasidone

D,aripiprazole

D8,safetyconcernsofantipsychoticdevelopment,including（）

ProlongationofAandQT/QTcintervals

B,dyskinesia（EPS/TD）andprolactinlevelswereelevated

C,weightgainandabnormalglucoseandlipidmetabolism

Doraboveiscorrect

D9,riskofsuddencardiacdeathinresponsetoantipsychoticdrugs,strategiesthatmaybetakeninclude

AandECGmonitoring

B,paycloseattentiontoprolongationofQTinterval

Candreduceotherriskfactorsforsuddencardiacdeath

Doraboveiscorrect

B10,whichcausesprolactintoincrease,isthemostobviousantipsychoticdrug

Aandclozapine

Bandrisperidone

C,KuiLiuping

D,aripiprazole

Standardizedtreatmentofantipsychoticdrugs

ThecharacteristicsofD1andaspirinare（）

Aand5-serotonin2Areceptorblocked

Bcanimprovenegativesymptomsandemotionalsymptoms

CandreducetheoccurrenceofEPS

Dandaboveareall

TheadverseeffectsofD2andantipsychoticdrugsweremainly（）

Aandmetabolicsyndrome

TheeffectsofBandprolactinlevels

Candextrapyramidaladversereactions

Dandaboveareall

B3,chronicpatienttreatmenterroris（）

A,first-linedrug,singledrug,sufficientfoottherapy

B,therecommendeddoseshouldbeuseddirectly

C,monotherapy,first-lineandsecond-linetherapiesarestillunsatisfactoryforcombinationtherapy

D,regularevaluationofcurativeeffecttoadjustthepositivetreatment

D4anddurationoftreatmentdescribedcorrectlyare（）

A,asappropriate,adjustthedose,takethepreventivedoseofrecurrence,anddonotchangethedrugasmuchaspossible

B,thecourseoftreatmentisgenerallynotlessthan2-5years

Cimprovesadherencetodrugmaintenancetherapy

Dandaboveareall

D5,featuresofschizophreniainclude（）

A,negativeandpositivesymptoms

B,attack,hostility

C,cognitiveimpairment

Dandaboveareall

C6whichofthefollowingisnotapositivesymptomofschizophrenia?

A,delusions

B,illusion

C,socialwithdrawal

D,speechdisorder

D7,acutephaseofschizophrenia,including（）

A,startingpatients

AcuteexacerbationsofBinchronicpatients

C,stableacuteexacerbationofthepatient

Dandaboveareall

D8,thepathologicalchangesinschizophreniaaredescribedascorrect

Aandthenumberandvolumeofdendriticspinesarereduced

ThenumberofBandglialcellsdecreased

C,axonterminalvolumereduced

Dandaboveareall

C9,atypicalantipsychotic,doesnotinclude（）

A,chlorpromazine

Bandperphenazine

Cziprasidone

D,ShuBili

D10,guidelinesforthepreventionandtreatmentofmentaldisordersinChinainclude

Aanddepressivedisorder

Bandanxietydisorders

C,dementia

Dandaboveareall

Commonproblemsandtreatmentofantidepressants

B1,thetypeSSRIdrugmostlikelytocausewithdrawalreactions,isthesuddendiscontinuationofthedrug

A,FuXiting

B,PaRossiDean

C,sertraline

D,citalopram

A2,anantidepressantthatblockscholinergicreceptorsandhistaminereceptors,doesnotproducesideeffects

A,extrapyramidalsideeffects

B,drymouth,constipation

C,dysuria,blurredvision

D,sedationandweightgain

WhatiswrongwithC3andbelowregardingmirtazapine'scontraindication?

A,patientswithsevereheart,liver,kidneydiseaseandlowwhitebloodcountwereusedwithcaution

Bshouldnotbeusedincombinationwithethanol,diazepam,andotherantidepressants

C,evenallergiescanalsobeused

DisforbiddentobeusedincombinationwithMAOIsandother5-HTactivators

D4,aneurotransmitterreceptorblockedbyantidepressants,includes（?

）

AandH1receptors

B,cholinergicMreceptor

C,A1adrenergicreceptors

Dandaboveareall

C5,theantidepressantonsettimeisusually（）

A,3days

BandZhou

C,2-4weeks

D,5-6weeks

D6andMAOIarepronetooccurwhencombinedwithother5-HTblockingdrugs

Aandmalignantsyndrome

Bandorthostatichypotension

ManicepisodesofC

Dand5-HTsyndrome

C7,theusualconsensusonthetreatmentofdepressionisthatpatientswithfirstattackcanbemaintained

A,4-6months

B,2-4weeks

C,6-8months

D,atleast3months

D8,antidepressanttreatmentconsolidationperiod,theoriginaldoseshouldbemaintainedatleast

A,halfamonth

B,3weeks

C,1-2weeks

D,4-6months

WhatiswrongwiththeclassificationofantidepressantsinC9andbelow?

A,doxepinandsecondaryamineofdesipramineandnortriptylineandmaprotilineistraditionalantidepressants

B,fluoxetine,PaRossiDean,andsertralinebelongtothenewfiveHTreuptakeinhibitors

C,VinRafaSinandduloxetinebelongtothenewfiveHTreuptakeinhibitors

DandPoseybelongtotheNEreuptakeinhibitors

D10,whichofthefollowingisnota