生物dna复制经典选择例题（Examples of classic selection of biological DNA replication）.docx

生物dna复制经典选择例题（Examples of classic selection of biological DNA replication）.docx

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生物dna复制经典选择例题（Examplesofclassicselectionof

biologicalDNAreplication）

Radio

In1.1958years,experimentsonMeselsonandStAhlusing15Nand14NlabeledEscherichiacoliDNAfirstdemonstratedwhichofthefollowingmechanisms?

A.DNAcanbecopied

TheB.DNAgenecanbetranscribedintomRNA

C.DNAgenecanbeexpressedasprotein

D.DNA'smechanismofsemiretainedreplication

E.DNAtotalretentionreplicationmechanism

2.DNAreplicatesinasemi-reservedmanner.WhathappensifafullylabeledDNAmoleculereplicatestwogenerationsinanon-radioactivesolution,producingfourDNAmolecules?

A.twomoleculesareradioactive,twomoleculesarenotradioactive

B.isradioactive

C.twointhechainhalfradioactive

D.oneoftwostrandshavingradioactivity

NoradioactivitywasfoundinE.

3.ifoneofthefollowingenzymesisabsent,oneofthenucleotidesonthereplicationforkcannotbeadded.Whatkindofenzymeisthis?

A.DNAsynthaseI（polymerizationactivity）

B.DNApolymerase（5'-3'exonucleaseactivity）

C.DNApolymeraseIII

D.DNAligase

E.DNApolymeraseII

4.whatistheeffectofthyminetwo,whichoccursinDNA,asamutation?

A.doesnotterminatereplication

B.isrepairedbyagroupofenzymesincludingligase

C.readbyshiftmutation

D.iscatalyzedbythyminetwoenzyme

CovalentbondsbetweenthyminestrandsonE.twostrandsofcomplementarynucleotides

Whichofthefollowingenzymesisnotneededfor5.DNAreplication?

A.DNAdirectedDNApolymerase.

B.DNAdirectedRNApolymerase

C.ligase

D.RNAdirectedDNApolymerase

E.helixenzyme（helieAse）,topologicalisomerase（topoisomerAse）andhelicase（gyrAse）.Hui@JiaoZi$/xueHuiEdu.Com

6.whichofthefollowingstatementsaboutthereproductionofDNAiswrong?

A.hasDNAdirectedRNApolymerasetoparticipate

B.hasRNAdirectedDNApolymerasetoparticipate

C.isasemireservedcopy

D.ismadefromfourkindsofdNTP

E.hasDNAdirectedDNApolymerasetoparticipate

When7.DNAreplicates,thesequence5'-TpApGpAp-3'willsynthesizethefollowingcomplementarystructures

A.5'-TpCpTpAp-3，

B.5'-ApTpCpTp-3，

C.5J-UpCpUpAp-3，

D.5'-GpCpGpAp-3，

E.3'-TpCpTpAp-3，

8.syntheticDNArawmaterialis

A.dAMPdGMPdCMPdTMP

B.dATPdGTPdCTPdTTP

C.dADPdGDPdCDPdTGP

D.ATPGTPCTPUTP

E.AMPGMPCMPUMP

9.whichofthefollowingistrueaboutthedescriptionofEscherichiacoliDNApolymeraseI?

A.hasa3'-5'exonucleaseactivity

B.hasanenzymeactivityof5'-3'endonuclease

C.

Proteinmodification

20.inDNAreplication,theroleofRNAprimersis

A.activatesDNApolymeraseIII

B.causesDNAdoublestrandstounravel

C.provides5〃end〃asasynthesis,newDNAchain,startingpoint,wisdom/Discussion&altar&XuEHui.Com

D.provides3〃0H〃asthestartingpointforthesynthesisofnewDNAchains

E.provides3〃0H〃asthestartingpointforthesynthesisofnewRNAchains.

Initiationof21.DNAreplication,participationfromthesupercoileddoublestrandedchainenzymeorunlockfactor

A.unwindingenzyme

B.topoisomeraseI

C.DNAbindingprotein.

D.initiatedprecursor

E.topoisomeraseii.

22.,thenatureoftelomeraseisone

A.DNApolymerase

B.RNApolymerase

C.DNAhydrolase

D.reversetranscriptase

E.ligase

23.abouttheroleofDNApolymeraseinDNAreplication,theerroris

TheA.substrateisdNTP

B.musthaveaDNAtemplate

ThesynthesisdirectionofC.canonlybe5'-3'

D.requiresATPandMgtoparticipate

E.causesDNAdoublestrandstounravel

24.,aboutEscherichiacoliDNApolymeraseIII,theerroristhat

A.catalyzestheattachmentofdNTPtothe5hydroxyendoftheDNAfragment

B.catalyzeddNTPwasattachedtoprimerchainsandcollectedbymedicaleducationnetwork

C.requiresfourdifferentdNTPasafunction

D.isanasymmetrictwodimercomposedofavarietyofsubunits

E.playsamajorroleinDNAreplicationinthelengtheningofthestrand

25.thefollowingdescriptionofEscherichiacoliDNApolymeraseisincorrect

A.DNApolIcanbedividedintotwofragmentsofsize

B.DNApolIIhas3',5'exonucleaseactivity

C.DNApolIIIplaysamajorroleinreplicationchainelongation

D.DNApolIIIconsistsoffoursubunits

E.actsastheagentwithfournucleosides

26.DNAreplicationinitiationprocessstatement,erroris

TheinitiationofA.involvesinitiationofenzymesandinitiationofprecursors

B.triggeredenzymesareaspecialkindofRNApolymerase

TheinitiationoftheC.followerchainissimplerthantheinitiationoftheleadingstrand

D.triggerprecursorcontainsmanyproteinfactors

TheprecursorandinitiatorcanbeassembledintoinitiatoranddissociatedbyE.

27.,thereasonforthelowreplicationerrorrateofDNAinprokaryotesisthattheexplanationiswrong

A.DNApolIhasa3'-5'exonucleaseactivity

B.DNApolIhasa5'-3'exonucleaseactivity,

BothC.DNApolIandIIIhaveendonucleaseactivity

D.DNApolIIIhas3'-5'exonucleaseactivity

E.DNApolIandIIIare3'-5'exonucleaseactivity

28.aboutthedescriptionofligaseinDNAreplication,theerroris

A.catalyzestheattachmentofadjacentDNAfragmentsto5',3，-phosphoricacidtwoesterbonds

B.connectionreactionsrequireATPorNADinvolvement

C.catalyzestheattachmentofadjacentDNAfragmentsto3',5'-phosphoricacidtwoesterbonds

D.participatesinthegenerationofthefollowerchain

E.

Inthecatalyticreaction,anintermediateisformedwithATP

29.okazakifragmentsrefersto

DNAfragmentontheA.DNAtemplate

DNAsegmentssynthesizedonB.strand

DNAfragmentssynthesizedonC.leadingstrand

SynthesisofRNAfragmentscatalyzedbyD.primers

E.synthesizedbyDNAligaseDNA.

30.thefollowingprocessrequiresDNAligaseis

A.DNAreplication

B.RNAtranscription

C.DNAfractureandmodification

MethylationofD.DNA

AcetylchemistryofE.DNA

When31.DNAreplicates,donotrequireanyofthefollowingenzymesinvolved?

A.DNAdirectedDNApolymerase

B.DNAligase

C.topoisomerase

D.unwindingenzyme

E.restrictionendonuclease

When32.DNAreplicates,themodeofsynthesisofprogenyDNAis

A.twochainsarediscontinuoussynthesis

B.twochainsarecontinuoussynthesis

C.twostrandsareasymmetrictranscriptionsynthesis

ThetwochainsofD.are3,5,andtwo

E.achain,5 3anotherchain3,‘5Jsynthesis

33.enzymesthatidentifythestartingpointofDNAreplicationaretheenzymesthat

A.DNApolymerase

B.DNAligase

C.primers

D.topoisomerase

E.unwindingenzyme

34.,aboutthesemidiscontinuoussynthesisofDNA,theerroneousstatementisthat...

TheA.leadingchainiscontinuouslysynthesized

TheB.chainoffollowersisdiscontinuouslysynthesized

TheC.fragmentisthediscontinuoussynthesisofOkazakifragments

HalfofthesynthesisoftheD.leadingchainandthefollowerchainisdiscontinuous

ThesynthesisoftheE.chainfollowsthesynthesisoftheleadingstrand

35.leadchainsarecontinuouslysynthesized,andstrandchainsarediscontinuouslysynthesized.LifescientistsareaccustomedtocallingthisDNAreplicationas

A.alldiscontinuousreplication

B.fullcontinuousreplication

C.allreservedreplication

D.semidiscontinuousreplication

E.noneoftheabove._Huieducationnetwork$@

36.comparingtheDNAreplicationofeukaryoteswithprokaryotes,thesimilaritiesbetweenthetwoarethat

ThelengthofA.primersisshorter

ThesynthesisdirectionofB.is5，-3'

C.Okazakifragmentlengthshort

D.hasmultiplereplicationstartpoints

E.DNAreplicationisslower（50nt/s）

37.enzymesinvolvedinprokaryoticDNAreplicationare

A.DNAPolalpha

B.DNAPolI

C.DNAPolgamma.

D.DNAPolDelta

E.DNAPolIII

38.enzymesinvolvedinprokaryoticDNArepairare

A.DNAPolalpha

B.DNAPolI

C.DNAPolgamma

D.DNAPolDelta

E.DNAPolIII

39.therepairofthedamagecausedbyUVirradiationinEscherichiacoliis

A.recombinationrepair

B.UvrABC

C.SOSrepair

D.DNAmethylationmodification

E.telomerase

40.chromosomeDNAtelomereshorteningandreducethedegradationistheway

A.recombinationrepair

B.UvrABC

c.

SOSrepair

D.DNAmethylationmodification

E.telomerase

41.eukaryoticchromosomeshavereversetranscriptioneffects

A.reversetranscriptase

B.telomerase

C.terminaltransferase

D.retrovirus

E.phagevirus

42.inDNAreplication,thecatalyticremovalofprimerstosupplementthevoidenzymeis

A.methyltransferase

B.ligase

C.primers

D.DNA.Poll

E.terminaltransferase

43.enzymesthatcatalyzetheformationoftwophosphatebondsadjacentto5'phosphategroupand3'hydroxylgroupinDNAare

A.methyltransferase

B.ligase

C.primers

D.DNAPolI

E.terminaltransferase

44.inDNAreplication,theenzymethatcatalyzesthesynthesisofprimersis

A.methyltransferase

B.ligase

C.primers

D.DNAPolI

E.terminaltransferase

45..Brownskindiseaseisakindoftransmittedskindiseaseinhumanbeings.Themolecularbasisofthisdiseaseisthatitis

A.cellmembranepermeabilitydefectscauserapiddehydration

B.inactivatetemperaturesensitiveenzymesinsunlight

C.wasinducedbyultravioletradiationtoinducevirulentpreviruses

D.cellsdonotsynthesizecarotenoidlikecompounds

ThereisadefectintheexcisionrepairsystemofthyminetwoonE.DNA

46.diseasesrelatedtotheDNArepairprocessarecollectedbythemedicaleducationnetwork

A.’sdryskindisease

B.porphyria

C.jaundice

D.xanthineurinedisease

E.gout

47.whatisthefollowingdescriptionaboutthecharacteristicsofmammalianDNAreplication?

A.RNAprimersweresmaller

B.Okazakifragmentssmaller

C.DNApolymerase,alpha,beta,andgammaareinvolved

D.hasonlyonestartingpointforreplication

WhenE.fragmentsareconnected,energyissuppliedbytheA